Timing Is Everything, Even for Cholinergic Control

Timing Is Everything, Even for Cholinergic Control

Synaptic plasticity is widely considered to be a cellular mechanism underlying learning and memory. In this issue of Neuron, Gu and Yakel show that the precise timing of a single cholinergic pulse of activity can determine whether plasticity will occur at a glutamatergic synapse and confer long-term potentiation versus depression.

Is Timing Everything?

Thank you Ben and AmSECT for organizing this conference. And thank you all for showing up on Saturday morning. My objectives for this presentation are to review the current knowledge of time spent below critical thresholds and more specifically the relationship between low oxygen delivery and organ function following cardiopulmonary bypass (CPB). Additionally, we will investigate the time–dose ...

Timing Is Everything?

Timing Is Everything

cated in depression of sensory responses in superficial layers of the cortex following whisker deprivation (Glazewski and Fox, 1996). To test whether the relative timing of pre-and postsynaptic activity has an effect Changes in sensory experience are capable of produc-on cortical plasticity, Feldman prepared slices of barrel ing changes in sensory transmission within the neocor-cortex and made ...

Timing Is Everything

: Timing Is Everything 1 β Yin and Yang of Myocardial Transforming Growth FactorPrint ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2005 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.0000167557.59069.D9 2005;111:2416-2417 Circulation. http://circ.ahajournals.org...